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NEET • BIOLOGY • MOLECULAR BASIS OF INHERITANCE

Molecular basis of inheritance practice · Mixed difficulty

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301 Hard
301 of 388
Remembering +4 | -1
Which one of the following is the starter codon?
View answer and explanation
Correct option: A
AUG
Option A (AUG) is correct because AUG is the start codon that initiates translation and codes for methionine.
302 Hard
302 of 388
Understanding +4 | -1
Assertion (A): The gene I codes for the repressor of the lac operon.

Reason (R): The y-gene codes for permease, which increases permeability of the cell to β\beta-galactosidase.
View answer and explanation
Correct option: C
(A) is true but (R) is false
Option C ((A) is true but (R) is false) is correct because the gene I codes for the repressor, but the y-gene codes for permease, which increases permeability of the cell to β\beta-galactosidase, not β\beta-galactosidase itself.
303 Medium
303 of 388
Remembering +4 | -1
In DNA structure, Nobel Prize was given to
View answer and explanation
Correct option: D
Watson and Crick
Option D (Watson and Crick) is correct because James Watson and Francis Crick received the Nobel Prize for their discovery of the structure of DNA.
304 Medium
304 of 388
Remembering +4 | -1
DNA sequence that code for protein are known as
View answer and explanation
Correct option: B
Exons
Option B (Exons) is correct because exons are the coding regions of DNA that are translated into proteins.
305 Medium
305 of 388
Understanding +4 | -1
Promoter in a transcription unit is located at
View answer and explanation
Correct option: C
51{5^1} end upstream of coding strand
Option C (51{5^1} end upstream of coding strand) is correct because the promoter is located at the 5' end upstream of the coding strand in a transcription unit.
306 Medium
306 of 388
Application +4 | -1
The base sequence in mRNA transcribed from DNA having base sequence 5′5^{\prime} CTTAG 3′3^{\prime} in its coding strand would be
View answer and explanation
Correct option: D
5' CUUAG 3'
Option D (5' CUUAG 3') is correct because mRNA is transcribed from the template strand, and the coding strand is identical to the mRNA sequence (with U replacing T).
307 Hard
307 of 388
Understanding +4 | -1
During infection of E.coli cells by bacteriophage T2,{T_2},
View answer and explanation
Correct option: D
Only nucleic acids enter the cell
Option D (Only nucleic acids enter the cell) is correct because the Hershey-Chase experiment demonstrated that only the DNA of the bacteriophage enters the E. coli cell during infection.
308 Medium
308 of 388
Understanding +4 | -1
In lac operon which gene transcribe mRNA for polypeptide synthesis.
View answer and explanation
Correct option: C
Structural gene
Option C (Structural gene) is correct because the structural genes (lacZ, lacY, lacA) are transcribed into a single mRNA molecule, which is then translated into the respective polypeptides.
309 Easy
309 of 388
Remembering +4 | -1
Which one of the following is correctly matched?
View answer and explanation
Correct option: A
Frederick Griffith - Discovered the phenomenon of transformation
Option A (Frederick Griffith - Discovered the phenomenon of transformation) is correct because Frederick Griffith's experiment demonstrated the transformation of bacteria.
310 Hard
310 of 388
Analyzing +4 | -1
In an E.coli strain ii gene gets mutated and its product can not bind the inducer molecule. If growth medium is provided with lactose, what will be the outcome?
View answer and explanation
Correct option: D
z, y, a genes will not be translated
Option D (z, y, a genes will not be translated) is correct because if the repressor cannot bind the inducer (lactose), it will remain bound to the operator, preventing transcription and therefore translation of the structural genes.
311 Medium
311 of 388
Remembering +4 | -1
Which of the following enzyme is used in DNA multiplication?
View answer and explanation
Correct option: D
DNA polymerase
Option D (DNA polymerase) is correct because DNA polymerase is the enzyme responsible for synthesizing new DNA strands by adding nucleotides to the 3' end of a growing strand.
312 Easy
312 of 388
Understanding +4 | -1
Sickle cell anaemia results from a single base substitution in a gene , thus it is example of
View answer and explanation
Correct option: A
Point mutation
Option A (Point mutation) is correct because sickle cell anemia results from a single base substitution, which is the definition of a point mutation.
313 Medium
313 of 388
Understanding +4 | -1
DNA can be formed by
View answer and explanation
Correct option: C
RNA dependent DNA polymerase
Option C (RNA dependent DNA polymerase) is correct because it describes the enzyme that synthesizes DNA using an RNA template.
314 Medium
314 of 388
Understanding +4 | -1
From his transformation experiment Griffith concluded with transforming principle might be?
View answer and explanation
Correct option: D
None
Option D (None) is correct because Griffith concluded that there was a transforming principle, but he didn't identify it as DNA. He only knew that something was being transferred from the heat-killed S strain to the R strain.
315 Hard
315 of 388
Understanding +4 | -1
In the formation of polynucleotide chain, the number of different types of nucleotides that participate are
View answer and explanation
Correct option: B
8
Option A is incorrect. In the formation of a polynucleotide chain using DNA, there are 4 different types of nucleotides that participate: Adenine, Guanine, Cytosine, and Thymine.
316 Medium
316 of 388
Analyzing +4 | -1
Assertion: RNA produced during transcription
in eukaryotic cells cannot be straight away used
in photosynthesis.

Reason: RNA splicing phenomena helps in the
removal of exons.
View answer and explanation
Correct option: C
If Assertion is true but Reason is false
Option C (If Assertion is true but Reason is false) is correct because RNA produced during transcription in eukaryotic cells needs processing, but RNA splicing removes introns, not exons.
317 Medium
317 of 388
Understanding +4 | -1
(A) : Retroviruses mutate and evolve faster

(R) : Retrovirus have RNA genome
View answer and explanation
Correct option: A
Both (A) and (R) are true and (R) is the correct explanation of (A)
Option A is correct because retroviruses mutate faster due to their RNA genome, which lacks proofreading mechanisms.
318 Medium
318 of 388
Remembering +4 | -1
Among the pyrimidines, this is common for both DNA and RNA?
View answer and explanation
Correct option: B
Cytosine
Option B (Cytosine) is correct because cytosine is a pyrimidine base found in both DNA and RNA.
319 Medium
319 of 388
Remembering +4 | -1
In bacterium, permease is located in?
View answer and explanation
Correct option: C
cell membrane
Option C is correct because permease is a membrane protein located in the cell membrane of bacteria.
320 Medium
320 of 388
Remembering +4 | -1
In bacterium E. Coli function of this is clearly not known?
View answer and explanation
Correct option: A
Transacetylase
Option A is correct because the function of transacetylase in E. coli is not clearly known.
321 Medium
321 of 388
Understanding +4 | -1
Choose the correct pair of RNA type and its function.
View answer and explanation
Correct option: B
rRNA – Plays catalytic role during translation
Option B (rRNA – Plays catalytic role during translation) is correct because rRNA, specifically within the ribosome, catalyzes the formation of peptide bonds during translation.
322 Easy
322 of 388
Application +4 | -1
The codon AUG codes for Methionine. What would be the base sequence on anti-codon loop of tRNA that would be amino acylated with this amino acid?
View answer and explanation
Correct option: D
5’ CAU 3’
Option D (5’ CAU 3’) is correct because the anticodon loop of tRNA is complementary and antiparallel to the codon AUG, hence it is 5' CAU 3'.
323 Hard
323 of 388
Understanding +4 | -1
Assertion: The uptake of DNA during transformation is an active, energy requiring process.

Reason: Transformation occurs only in those bacteria, which possess the enzymatic machinery involved in the active uptake and recombination.
View answer and explanation
Correct option: A
If both assertion and reason are true and reason is the correct explanation of assertion
Option A (If both assertion and reason are true and reason is the correct explanation of assertion) is correct because the uptake of DNA during transformation requires specific enzymatic machinery and energy expenditure, making the reason a valid explanation for the assertion.
324 Medium
324 of 388
Analyzing +4 | -1
Identify the statements pertaining to the regulatory genes (R), associated with the lac operon that are incorrect.

(i) mRNA is transcribed from the R gene whether lactose is present or not.

(ii) mRNA is transcribed from the R gene only when the lactose is present.

(iii) mRNA is transcribed from the R gene only when the lactose is not present.

(iv) Lactose inhibits the translation or R gene mRNA.
View answer and explanation
Correct option: D
(ii), (iii) and (iv)
Option D ((ii), (iii) and (iv)) is correct because the regulatory gene (R) is transcribed constitutively (always), and lactose does not inhibit its translation.
325 Medium
325 of 388
Application +4 | -1
RNA formed from the transcription of DNA has base sequence 5′5^{\prime} AUUAUGAAA 3′3^{\prime}. What would be the sequence of coding strand of DNA?
View answer and explanation
Correct option: C
5' ATTATGAAA 3'
Option C (5' ATTATGAAA 3') is correct because the coding strand of DNA has the same sequence as the RNA transcript, except T replaces U.
326 Medium
326 of 388
Understanding +4 | -1
DNA replication is
(A) Polymerization of nucleotides by DNA-dependent DNA polymerase activity
(B) Energetically very expensive process.
(C) Polymerization of ribonucleotides in 5'→3' direction
View answer and explanation
Correct option: B
Only (A) and (B) is correct
Option B is correct because DNA replication involves polymerization by DNA-dependent DNA polymerase and is energetically expensive.
327 Medium
327 of 388
Remembering +4 | -1
hn\mathrm{hn}RNA undergoes two additional processing. Out of which, in one of them an unusual nucleotide (methyl guanosine triphosphate) is added to the 5’ – end of hn\mathrm{hn} RNA. This is known as
View answer and explanation
Correct option: A
Capping
Option A (Capping) is correct because it describes the addition of methyl guanosine triphosphate to the 5' end of hnRNA.
328 Medium
328 of 388
Remembering +4 | -1
In the structure of polynucleotide chain, phosphoester linkage joins
View answer and explanation
Correct option: B
A phosphate group to nucleoside
Option B (A phosphate group to nucleoside) is correct because the phosphoester linkage connects a phosphate group to the sugar (nucleoside) in the polynucleotide chain.
329 Easy
329 of 388
Remembering +4 | -1
Which of the following types of RNAsRNAs plays both structural and catalytic role during translation?
View answer and explanation
Correct option: B
rRNArRNA
Option B (rRNArRNA) is correct because ribosomal RNA (rRNA) forms the structural framework of ribosomes and also catalyzes peptide bond formation during translation.
330 Medium
330 of 388
Remembering +4 | -1
Ribose sugar is present in
View answer and explanation
Correct option: D
RNA and ATP
Option D (RNA and ATP) is correct because ribose sugar is a component of both RNA and ATP molecules.
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