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NEET • BIOLOGY • MOLECULAR BASIS OF INHERITANCE
Molecular basis of inheritance practice · Mixed difficulty
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Showing 1-30 of 388 questions
1
Hard
1 of 388
Remembering
+4 | -1
The correct sequence of the first six amino acids in HbA beta globulin peptide is
View answer and explanation
Correct option: A
Valine – Histidine – Leucine – Threonine – Proline – Glutamic acid
Option A is correct because the correct sequence of the first six amino acids in the HbA beta-globin peptide is Valine - Histidine - Leucine - Threonine - Proline - Glutamic acid.
2
Medium
2 of 388
Analyzing
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Assertion: The bacteria and other prokaryotes
show high adaptability to the changing
environment.
Reason: Member of kingdom Monera are
efficient in regulating gene expression.
show high adaptability to the changing
environment.
Reason: Member of kingdom Monera are
efficient in regulating gene expression.
View answer and explanation
Correct option: A
If both Assertion and Reason are true and
Reason is the correct explanation of Assertion
Reason is the correct explanation of Assertion
Option A is correct because both the assertion and reason are true, and the reason correctly explains why prokaryotes are highly adaptable.
3
Easy
3 of 388
Understanding
+4 | -1
Which of the following is not true for DNA polymerase?
View answer and explanation
Correct option: D
Can add nucleotide at 5' end
Option D is correct because DNA polymerase can only add nucleotides to the 3' end of a growing DNA strand, not the 5' end.
4
Medium
4 of 388
Remembering
+4 | -1
Dystrophin gene consists of
View answer and explanation
Correct option: B
2.4 million bases
Option B (2.4 million bases) is correct because the dystrophin gene is known to consist of approximately 2.4 million bases.
5
Easy
5 of 388
Understanding
+4 | -1
Read the following four statements (i-iv).
i. In transcription, adenosine pairs with uracil.
ii. Regulation of lac operon by repressor is referred to as positive regulation
iii. The human genome has approximately 30,000 genes
iv. Haemophilia is a sex-linked recessive disease
How many of the above statements are correct?
i. In transcription, adenosine pairs with uracil.
ii. Regulation of lac operon by repressor is referred to as positive regulation
iii. The human genome has approximately 30,000 genes
iv. Haemophilia is a sex-linked recessive disease
How many of the above statements are correct?
View answer and explanation
Correct option: A
Two
Option A is correct because statements (i) and (iv) are correct. Adenosine pairs with uracil in transcription, and hemophilia is a sex-linked recessive disease.
6
Medium
6 of 388
Understanding
+4 | -1
Reactive group of RNA is?
View answer and explanation
Correct option: C
group
Option C ( group) is correct because the presence of a hydroxyl group at the 2' position of the ribose sugar in RNA makes it more reactive compared to DNA.
7
Medium
7 of 388
Remembering
+4 | -1
The following codon do not code for any amino acid?
View answer and explanation
Correct option: D
All
Option D (All) is correct because UAA, UGA, and UAG are all stop codons that do not code for any amino acid.
8
Medium
8 of 388
Understanding
+4 | -1
During the process of gene amplification using PCR, if very high temperature is not maintained in the beginning, then which of the following steps of PCR will be affected first?
View answer and explanation
Correct option: A
Denaturation
Option A (Denaturation) is correct because denaturation, the separation of DNA strands, requires high temperatures at the beginning of PCR.
9
Easy
9 of 388
Remembering
+4 | -1
Some rRNA function as catalyst. These are called
View answer and explanation
Correct option: A
Ribozyme
Option A (Ribozyme) is correct because some rRNA molecules possess catalytic activity and are therefore classified as ribozymes.
10
Medium
10 of 388
Analyzing
+4 | -1
Assertion : In a DNA molecule, A–T rich parts
melt before G–C rich parts.
Reason : In between A and T there are three
H–bond, whereas in between G and C there are
two H-bonds.
melt before G–C rich parts.
Reason : In between A and T there are three
H–bond, whereas in between G and C there are
two H-bonds.
View answer and explanation
Correct option: C
If Assertion is true but Reason is false
Option C (If Assertion is true but Reason is false) is correct because A-T rich parts melt before G-C rich parts, but this is due to having two hydrogen bonds instead of three.
11
Easy
11 of 388
Understanding
+4 | -1
Which of the following statements are true regarding Griffith’s Experiment?
I. Biochemical nature of genetic material is known.
II. Experimental bacteria is Streptococcus.
III. Heat killed virulent bacteria is transformed.
IV. S strain is virulent as it lacks capsule.
I. Biochemical nature of genetic material is known.
II. Experimental bacteria is Streptococcus.
III. Heat killed virulent bacteria is transformed.
IV. S strain is virulent as it lacks capsule.
View answer and explanation
Correct option: C
Only II
Option C (Only II) is correct because only statement II is true regarding Griffith's experiment. The experimental bacteria was Streptococcus.
12
Medium
12 of 388
Remembering
+4 | -1
The sequence of structural genes in lace operon is?
View answer and explanation
Correct option: D
Z, Y, A
Option D is correct because the structural genes in the lac operon are arranged in the order: lacZ, lacY, and lacA, which code for β-galactosidase, permease, and transacetylase, respectively.
13
Easy
13 of 388
Understanding
+4 | -1
State true (T) or false (F) for the given statements and choose the correct option.
a. The lac operon consists of two regulatory genes and four structural genes.
b. The y gene codes for permease, which increases permeability of the cell to -galactosides.
a. The lac operon consists of two regulatory genes and four structural genes.
b. The y gene codes for permease, which increases permeability of the cell to -galactosides.
View answer and explanation
Correct option: C
a-F, b-T
Option C is correct because statement a is false (lac operon has one regulatory gene and three structural genes), and statement b is true (y gene codes for permease).
14
Medium
14 of 388
Understanding
+4 | -1
If a geneticist uses the blind approach for sequencing the whole genome of an organism, followed by assignment of function to different segments, the methodology adopted by him is called as:
View answer and explanation
Correct option: B
Sequence annotation
Option B (Sequence annotation) is correct because sequence annotation involves assigning functions to different segments of a genome after sequencing it.
15
Easy
15 of 388
Remembering
+4 | -1
In RNA, which is absent?
View answer and explanation
Correct option: C
Thymine
Option C (Thymine) is correct because thymine is a nitrogenous base found in DNA but is replaced by uracil in RNA.
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16
Easy
16 of 388
Understanding
+4 | -1
Identify the correct statements
View answer and explanation
Correct option: C
Sequence annotation – correlating sequence of nucleotides already known for an organism to their functions
The correct answer is C (Sequence annotation – correlating sequence of nucleotides already known for an organism to their functions) because sequence annotation is the process of assigning biological functions to DNA sequences.
17
Hard
17 of 388
Understanding
+4 | -1
Assertion (A): DNA serves as hereditary material.
Reason (R): DNA functions as blueprint for building and running cellular machinery.
Reason (R): DNA functions as blueprint for building and running cellular machinery.
View answer and explanation
Correct option: A
Both (A) & (R) are true and the (R) is the correct explanation of the (A)
Option A is correct. DNA serves as hereditary material (Assertion), and it functions as a blueprint for building and running cellular machinery (Reason), making the Reason the correct explanation for the Assertion.
18
Medium
18 of 388
Remembering
+4 | -1
There is no DNA?
View answer and explanation
Correct option: A
Mature RBC
Option A (Mature RBC) is correct because mature red blood cells lack a nucleus and therefore do not contain DNA.
19
Medium
19 of 388
Understanding
+4 | -1
DNA fingerprinting refers to
View answer and explanation
Correct option: A
Molecular analysis of profiles of DNA samples
Option A (Molecular analysis of profiles of DNA samples) is correct because DNA fingerprinting involves analyzing the unique DNA profiles of individuals.
20
Easy
20 of 388
Remembering
+4 | -1
Which of the following sugars is found in nucleic acid?
View answer and explanation
Correct option: D
Deoxyribose
Option D (Deoxyribose) is correct because deoxyribose sugar is a component of DNA, which is a nucleic acid.
21
Hard
21 of 388
Understanding
+4 | -1
A codon specifies the same amino acid in Brassica and Homo sapiens because codons are
View answer and explanation
Correct option: C
Universal
Option C (Universal) is correct because the genetic code is universal, meaning the same codons specify the same amino acids in almost all organisms.
22
Medium
22 of 388
Application
+4 | -1
A gene encoding for a polypeptide of 60 amino acids get mutated at 30 th codon UAU becoming UAA. The result would be
View answer and explanation
Correct option: A
A polypeptide of 29 amino acids
Option A (A polypeptide of 29 amino acids) is correct because the mutation creates a stop codon (UAA) at the 30th codon position, prematurely terminating translation.
23
Medium
23 of 388
Analyzing
+4 | -1
Assertion: Viruses having shorter life span, mutate and evolve faster.
Reason: Viruses have generally RNA genome.
Reason: Viruses have generally RNA genome.
View answer and explanation
Correct option: A
If both the assertion and the reason are true and the reason is a correct explanation of the assertion
Option A is correct because viruses with shorter lifespans and RNA genomes mutate and evolve faster due to the lack of proofreading mechanisms in RNA replication.
24
Medium
24 of 388
Understanding
+4 | -1
Lac I gene of Lac operon
View answer and explanation
Correct option: A
Has a binding site for repressor protein
Option A is correct because the lac I gene has a binding site for the repressor protein.
25
Easy
25 of 388
Application
+4 | -1
The distance between two consecutive base pairs is , what will be the length of DNA double helix in a diploid human cell?
View answer and explanation
Correct option: B
2.2 meters
Option B (2.2 meters) is correct because the length of DNA in a diploid human cell is calculated by multiplying the number of base pairs by the distance between them.
26
Hard
26 of 388
Remembering
+4 | -1
In sickle cell anemia glutamic acid is replaced by valine. Which one of the following are triplets codes for valine?
View answer and explanation
Correct option: D
GUG
Option D is correct because GUG is one of the codons that codes for valine, which replaces glutamic acid in sickle cell anemia.
27
Hard
27 of 388
Understanding
+4 | -1
Assertion (A): The sensitivity of fingerprinting technique has been increased by the use of PCR.
Reason (R): DNA from a single cell is not enough to perform DNA finger printing analysis.
Reason (R): DNA from a single cell is not enough to perform DNA finger printing analysis.
View answer and explanation
Correct option: C
(A) is true but (R) is false
Option C is correct because the assertion is true, but the reason is false. PCR allows DNA fingerprinting from even a single cell.
28
Medium
28 of 388
Remembering
+4 | -1
DNA acts as a template for synthesis of
View answer and explanation
Correct option: C
Both (a) and (b)
Option C (Both (a) and (b)) is correct because DNA serves as a template for both RNA (transcription) and DNA (replication) synthesis.
29
Medium
29 of 388
Understanding
+4 | -1
In a mRNA molecule, untranslated regions are present at?
View answer and explanation
Correct option: C
Both 1 and 2
Option C (Both 1 and 2) is correct because untranslated regions (UTRs) are present at both the 5' end (before the start codon) and the 3' end (after the stop codon) of mRNA molecules.
30
Medium
30 of 388
Understanding
+4 | -1
Side by side experiments are conducted to identify DNA as genetic material, unequivocally by?
View answer and explanation
Correct option: C
Hershy and Chase
Option C (Hershy and Chase) is correct because their experiment using radioactive isotopes of phosphorus and sulfur definitively proved that DNA, not protein, is the genetic material.
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