Molecular basis of inheritance practice · Mixed difficulty

Consider these following sentences and choose the correct ones

I. Each gene contains a specific promoter region and a leader sequence for guiding the beginning of transcription.

II. Only one strand of DNA, called template strand is copied by RNA polymerase this strand runs in 3 ' 5' direction.

III. RNA polymerase adds complementary nucleotides forming single strand mRNA in $3^{\prime} 5^{\prime}$ 'direction.

IV. Section of DNA that has been transcribed is rewound into its original configuration.

Which of the following step shows transformation w.r.t. Griffith Experiment.

Assertion (A): HGP was closely associated with the rapid development of a new area in biology called as Bioinformatics.

Reason (R): The enormons amount of data generated in HGP necessitated the use of high speed computational devices for data storage & analysis.

When DNA replication starts

DNA is denatured by

Assertion (A): The VNTR belongs to a class of satellite DNA referred to as mini-satellite.

Reason (R): The mini-satellite numbers remains same from chromosome to chromosome in an individual.

Which one of the following pairs of term/names means one and the same thing?

Which of the following strains of Pneumococcus when injected to mice will cause death of that mice?

Which of the following statements about HGP are correct:
a) Two major approaches expressed sequence tags and sequence annotation are used in HGP.
b) Fredrick sanger developed the method for determination of amino acid sequences in proteins.
c) Chromosome 1 was the first human chromosome to be sequenced.
d) More than 98% of the genome do not codes for any proteins.
e) Total number of genes estimated is 3000.

In eukaryotic transcription, heteronuclear RNA (hnRNA) is transcribed by

If a length of DNA has 45,000 base pairs, how many complete turns will the DNA molecule takes?

$(-)$ sign and $(+)$ sign for DNA strand stands for

Synthesis of proteins from the mRNA is called?

Select the incorrect statements from the following

(a) There are the evidences that $DNA$ was the first gentic material in the history of life.

(b) No $RNA$ acts as catalyst

(c) $DNA$ replication is said to be semiconservative as it has two strands of polynucleotide chain.

(d) A nitrogenous base is linked to the pentose sugar through ${N}$-glycosidic linkage.

The initiator codon is

Which of the following is not required for any of the techniques of DNA fingerprinting available at present?

Genetic material in most of the organisms?

DNA replication includes

The Human Genome Project was a _____ project coordinated by the U.S. Department of Energy and the National Institute of Health.

If the sequence of nucleotides on mRNA is known, the sequence of amino acids can be predicted but if the sequence of amino acids is known the exact sequence of nucleotides in mRNA cannot be predicted. This is because genetic code is

In a double helix of DNA molecule of 10 coils, if there are 30 adenine nitrogen bases, what is the number of guanine nitrogen bases?

Which RNAs pick up specific amino acid from amino acid pool in the cytoplasm to ribosome during protein synthesis?

During the replication of DNA, the synthesis of DNA on lagging strand takes place in segments. These segments are called

Assertion (A): The repetitive DNA are separated from bulk genomic DNA as different peaks during density gradient centrifugation.

Reason (R): The bulk DNA form a minor peak & other major peaks are referred to as satellite DNA.

During post-transcriptional processing, ______ is added to the 5' – end of hnRNA. Select the correct option to fill in the blank.

During protein synthesis, ribosome is found to be performing which of the following jobs?

Assertion: By switching the position of promoter with terminator the direction of transcription and the type of protein translated can be changed.
Reason: The promoter in a transcription unit defines the template and coding strands and it provides binding site for RNA polymerase.

Induced mutations has been used in mung bean for incorporating resistance to

Meselson and Stahl experiment proved

In 1944, Avery, McCarty and Macleod isolated a substance frorn heat killed virulent form of bacteria and added to nonvirulent form of bacteria which changed the non-virulent to virulent from this substance can be distroyed by