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NEET UG BIOLOGY MCQ: MOLECULAR BASIS OF INHERITANCE

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Understanding +4 | -1
DNA is a polymer of nucleotides are linked to each other by 3′−5′3' - 5' phosphodiester bond. To prevent polymerisation of nucleotides, which of the following modifications would you choose?
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Correct option: B
Remove / Replace 3′OH3'\mathrm{OH} group in deoxyribose
Option B is correct because the 3' OH group is essential for forming the phosphodiester bond during nucleotide addition; removing or replacing it would prevent polymerization.

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